Course intro
High level introduction of NMR
Share your NMR problems with me!
NMR active nuclei
Quiz – NMR active nuclei
Nuclei in an external magnetic field
Quiz - Nuclei in an external magnetic field
Nuclear shielding
Quiz - Nuclear shielding
The chemical shift
Symmetry in NMR
Quiz - Symmetry in NMR
Diamagnetic anisotropy
The Inductive effect
The integration of NMR spectra
Quiz – Proton NMR basics
Splitting
The coupling constant
Coupling to multiple partners
Coupling to multiple partners - drawing
How many signals and integral?
Proton NMR examples
Distinguish between compounds by NMR
Proton NMR examples - disubstituted benzenes
Magnetic (in)equivalence
Proton NMR summary
Analyzing the NMR spectrum
Quiz – Analyzing the NMR spectrum
Why is it called "upfield"?
Proton NMR ecercises
Carbon chemical shifts
Carbon NMR examples
DEPT-135 examples
Carbon NMR summary
Quiz - Carbon NMR summary
Carbon NMR ecercises
Who is your neighbor? - The COSY experiment
Who do you feel closest to? - The HSQC experiment
HSQC - Proton and carbon assignment of Atenolol
Assignment 1. - Deduce a structure having the molecular weight, proton and carbon spectra
Assignment 1. - Solution
Assignment 2. - Deduce a structure having the proton, carbon and DEPT spectra
Assignment 2. - Solution
Assignment 3. - Deduce a structure having the proton, carbon and DEPT spectra
Assignment 3. - Solution
Assignment 4. - Assign a structure having the proton, carbon and DEPT spectra
Assignment 4. - Solution
Assignment 5. - Assign a structure having the proton, carbon and DEPT spectra
Assignment 5. - Solution
